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The term “pharmacokinetics” is used to describe the scientific study of how drugs are metabolised in the human body following administration.

Here is a mnemonic that will help you to easily remember the factors  affecting the pharmacokinetics

Factors affecting drug pharmacokinetics:

  • Distribution: how the drug is distributed throughout the body, including factors such as protein binding, tissue permeability, and blood flow.
  • Absorption rate: how quickly and completely the drug is absorbed into the bloodstream from the site of administration.

  • Metabolism: how the drug is metabolized or broken down in the body, typically in the liver, into inactive or active metabolites.

  • Age: how the age of the patient can affect drug pharmacokinetics, such as changes in metabolism and excretion rates.
  • Gender: how gender can affect drug pharmacokinetics, such as differences in body composition, hormone levels, and enzyme activity.
  • Elimination: how the drug is eliminated from the body, either through the kidneys in urine or through the liver in feces or bile
  • Disease state: how the presence of disease can affect drug pharmacokinetics, such as changes in organ function or blood flow.
  • Body weight: how body weight can affect drug pharmacokinetics, such as differences in blood volume and tissue distribution.

  • Route of administration: the method by which the drug is administered (e.g., oral, intravenous, intramuscular, subcutaneous, transdermal).

  • Drug-drug interactions: how other drugs being taken by the patient can affect drug pharmacokinetics, such as changes in metabolism or elimination rates

Mnemonic: DAMAGED  BReaD

Mind Map / Concept Map /Memory Aid/ Mnemonic To Remember Factors Affecting Drug Pharmacokinetics

Dr. Arin Nandi

Passionate About Medical Science & Helping Future Doctors Achieve Top Ranks In Medical Exams. He is professionally a dentist as well as a public health expert from JIPMER (1), (2)working in health department
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