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Here is a quick mnemonic “IDIOPATHIC to remember about Stevens-Johnson Syndrome Rash

This can be valuable for patients as well as medical doctors, nurses & students doing their clinical rounds. You can also find it very useful for med exams like USMLE, NEET PG, FMGE, NExT & NCLEX exams

Stevens-Johnson Syndrome Rash : How To Remember Easily ?

  • I – Infection can be a cause of Stevens-Johnson syndrome.

  • D – Drugs, such as allopurinol, anticonvulsants, and antibiotics, can also trigger the syndrome in about 80% of cases.

  • I – Idiopathic factors, meaning unknown causes, can contribute to the development of Stevens-Johnson syndrome.

  • O – Overlapping conditions like SJS/TEN involve 10-30% of the epidermis, while SJS itself affects less than 10%.

  • P – Progression of the syndrome may involve erythematous and purpuric macules, bullae, sloughing, necrosis of the entire epidermis, and Nikolsky’s sign.

  • A – Among children, Stevens-Johnson syndrome is uncommon but more prevalent among patients with HIV infection, systemic lupus erythematosus, certain HLA types, or slow acetylators.

  • T – TEN, or toxic epidermal necrolysis, represents the most severe form of the syndrome with over 30% epidermal necrosis.

  • H – Hydration and prevention of sepsis are crucial due to the risk of dehydration and compromised skin integrity.

  • I – Integumentary complications can lead to mortality rates of up to 30% in Stevens-Johnson syndrome.

  • C – Children with Stevens-Johnson syndrome tend to have lower prevalence, while certain risk factors like HIV infection and systemic lupus erythematosus increase the chances.



Dr. Arin Nandi

Passionate About Medical Science & Helping Future Doctors Achieve Top Ranks In Medical Exams. He is professionally a dentist as well as a public health expert from JIPMER (1), (2)working in health department