Sleep-Wake Cycles Are Driven By Homeostatic, Allostatic, And Circadian Inputs Mnemonic

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Here is a quick mnemonic “SLEEP DRIVE END“ to remember about Sleep-Wake Cycles Are Driven By Homeostatic, Allostatic, And Circadian Inputs

This can be valuable for patients as well as medical doctors, nurses & students doing their clinical rounds. You can also find it very useful for med exams like USMLE, MBBS, NEET PG, FMGE, NExT, MCAT & NCLEX exams

Sleep-Wake Cycles Are Driven By Homeostatic, Allostatic, And Circadian Inputs: How To Remember Easily ?

  • S – Sleep drive increases with prolonged wakefulness.
  • L – Levels of adenosine rise in the brain during wakefulness.
  • E – Excitatory outputs from limbic areas contribute to anxiety about insomnia.
  • E – Excitatory outputs from limbic areas affect the arousal system.
  • P – Prostaglandin D2 is implicated in the sleep-promoting process.
  • D – Deeper slow-wave sleep occurs after the increase in sleep drive.
  • R – Receptors in the brain, such as A1 and A2a, are involved in sleep regulation.
  • I – Insomnia is common in patients with anxiety and psychiatric disorders.
  • V – Ventrolateral preoptic nucleus contains sleep-promoting neurons.
  • E – Excitatory outputs from the limbic system impact the need for sleep.
  • E – Excitatory outputs from the limbic system form a vicious cycle of anxiety.
  • N – Neurochemistry of sleep homeostasis is partially understood.
  • D – Drugs and behavioral approaches can be used to treat insomnia.

Mnemonic : SLEEP DRIVE END

Dr. Arin Nandi

Passionate About Medical Science & Helping Future Doctors Achieve Top Ranks In Medical Exams. He is professionally a dentist as well as a public health expert from JIPMER (1), (2)working in health department
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