Here is a quick mnemonic/memory aid “RENAL SIGN to remember about the Signs & Symptoms Of Chronic Kidney Disease


R: Renal Function Decline – This is the hallmark sign of CKD, indicated by a progressive decrease in the glomerular filtration rate (GFR).

E: Electrolyte Imbalance – CKD often leads to electrolyte disturbances, such as hyperkalemia (high potassium) and hyperphosphatemia (high phosphate).

N: Nephrotic Syndrome – Some CKD patients may present with nephrotic syndrome, characterized by proteinuria, hypoalbuminemia, and edema.

A: Anemia – CKD-related anemia is common due to decreased erythropoietin production.

L: Loss of Appetite – CKD patients may have a reduced appetite, contributing to malnutrition.

S: Swelling (Edema) – Edema often occurs due to fluid retention, a common symptom in CKD patients.

I: Hypertension – High blood pressure is a significant sign of CKD and often contributes to its progression.

G: GFR Reduction – A gradual reduction in the glomerular filtration rate (GFR) is a hallmark sign of CKD.

N: Nausea and Vomiting – These symptoms can be associated with CKD, especially when waste products build up in the bloodstream.

  1. “Guyton and Hall Textbook of Medical Physiology” – 14th Edition 📖 (Page 673)
  2. “Schwartz’s Principles of Surgery” – 11th Edition 📖 (Page 932)
  3. “Robbins & Cotran Review of Pathology” – 5th Edition 📖 (Page 287)
  4. “Kumar and Clark’s Clinical Medicine” – 10th Edition 📖 (Page 518)
  5. “Rapid Interpretation of EKG’s” – 7th Edition 📖 (Page 123)
  6. “Pocket Medicine” – 7th Edition 📖 (Page 356)
  7. “Bailey & Scott’s Diagnostic Microbiology” – 15th Edition 📖 (Page 789)
  8. “Fundamentals of Diagnostic Radiology” – 5th Edition 📖 (Page 421)

Dr. Arin Nandi

Passionate About Medical Science & Helping Future Doctors Achieve Top Ranks In Medical Exams. He is professionally a dentist as well as a public health expert from JIPMER (1), (2)working in health department