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Here is a quick mnemonic “CIRCADIAN RHYTHm to remember about Physiology Of Circadian Rhythmicity

This can be valuable for patients as well as medical doctors, nurses & students doing their clinical rounds. You can also find it very useful for med exams like USMLE, MBBS, NEET PG, FMGE, NExT, MCAT & NCLEX exams

Physiology Of Circadian Rhythmicity: How To Remember Easily ?

  • C – Circadian rhythms are the most evident in the wake-sleep cycle.
  • I – Important to distinguish between diurnal components and circadian rhythms.
  • R – Rhythmic variations occur in various physiological functions.
  • C – Cells have self-sustaining feedback loops driving circadian rhythmicity.
  • A – All tissues except SCN struggle to maintain long-term synchronization.
  • D – Destruction of the SCN results in a loss of circadian rhythms.
  • I – Intrinsically photosensitive ganglion cells synchronize the neural oscillator.
  • A – Age-related changes in sleep-wake timing may be due to homeostatic sleep regulation.
  • N – Night-shift workers and travelers can experience health problems due to misalignment.
  • R – Rhythm for wake propensity peaks before bedtime, while sleep propensity peaks near wake time.
  • H – Habitual sleep and wake times oppose sleep and wake tendencies.
  • Y – Your desired wake-sleep cycle should align with the endogenous circadian pacemaker.
  • T – Timing and internal architecture of sleep are coupled to the circadian pacemaker.
  • H – Health problems can arise from misalignment of the pacemaker.
  • M – (blank)


Dr. Arin Nandi

Passionate About Medical Science & Helping Future Doctors Achieve Top Ranks In Medical Exams. He is professionally a dentist as well as a public health expert from JIPMER (1), (2)working in health department