Medical Mnemonic _ Down Syndrome Pathology

Abnormal cell division leads to an excess of chromosome 21 DNA, which results in the genetic disorder known as Down’s syndrome. Distinct facial features, intellectual disability, and developmental delays are all hallmarks of Down’s syndrome.


How To Remember Down Syndrome Pathology ?

Down Syndrome Pathology :

  • Decreased alpha-fetoprotein and unconjugated estriol (maternal)
  • One extra chromosome (Trisomy 21)
  • Women of advanced age
  • Nondisjunction during maternal meiosis


Mnemonic: “DOWN


Mind Map / Concept Map /Memory Aid/ Mnemonic To Remember Down Syndrome Pathology


Remember this for your NExT Medical Exit Test exam & USMLE, Pre-Med, NCLEX exams.

Dr. Arin Nandi

Passionate About Medical Science & Helping Future Doctors Achieve Top Ranks In Medical Exams. He is professionally a dentist as well as a public health expert from JIPMER (1), (2)working in health department