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Here is a quick mnemonic “FATIGUE TREATMENT to remember about Fatigue Treatment

This can be valuable for patients as well as medical doctors, nurses & students doing their clinical rounds. You can also find it very useful for med exams like USMLE, NEET PG, FMGE, NExT & NCLEX exams

Fatigue Treatment : How To Remember Easily ?

  • F – Fatigue treatment starts with addressing the underlying disorder or disorders that contribute to fatigue.
  • A – Antidepressants may be helpful in treating chronic fatigue when symptoms of depression are present.
  • T – Therapy options such as cognitive-behavioral therapy have shown to be beneficial for managing fatigue in conditions like ME/CFS and cancer-related fatigue.
  • I – Increasing physical activity gradually through graded exercise therapy can improve walking times and reduce fatigue.
  • G – Graded exercise therapy can be effective by gradually increasing physical activity levels while considering target heart rates to avoid overexertion.
  • U – Understanding the potential contributors to fatigue is crucial, as it may have multifactorial causes in some cases.
  • E – Certain psychostimulants like amphetamines, modafinil, and armodafinil can help increase alertness and concentration, thereby reducing excessive daytime sleepiness.
  • T – Treating fatigue in patients with low vitamin D status may lead to improvement in their symptoms through vitamin D replacement.
  • R – Research on the biologic basis of fatigue is limited, hindering the development of more effective therapies.
  • E – Exploring the role of proinflammatory cytokines like interleukin 1α and 1β and tumor necrosis factor α in mediating fatigue may provide insights for future treatments.
  • A – Although preliminary studies suggest benefits, biologic therapies targeting cytokines have not consistently improved fatigue in clinical trials.
  • T – Targeting specific cytokines with antagonists could be a potential future approach for managing fatigue in certain patients.
  • M – More research is needed to understand how fatigue is detected and registered in the nervous system to develop better treatment strategies.
  • E – Evaluating and addressing the presence of other potential contributors to fatigue is important, especially in chronic illnesses.
  • N – Not all traditional disease-modifying therapies are effective in managing fatigue, highlighting the need for alternative approaches.
  • T – The primary priority in fatigue treatment is to address the underlying disorders that cause fatigue, as it can be curative in some cases.


Dr. Arin Nandi

Passionate About Medical Science & Helping Future Doctors Achieve Top Ranks In Medical Exams. He is professionally a dentist as well as a public health expert from JIPMER (1), (2)working in health department