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Here is a quick mnemonic “ONSET OF CYANOSIS to remember about Evaluation Of Cyanosis

This can be valuable for patients as well as medical doctors, nurses & students doing their clinical rounds. You can also find it very useful for med exams like USMLE, NExT Medical Step 1&2, MBBS, NEET PG, INI-CET, FMGE,MCAT & NCLEX exams

Evaluation Of Cyanosis : How To Remember Easily ?

  • O – Onset of cyanosis: Determine the time when cyanosis began.
  • N – Newborn or infancy: Cyanosis since birth or infancy indicates congenital heart disease.
  • S – Systems differentiation: Differentiate between central and peripheral cyanosis to identify respiratory or cardiovascular disorders.
  • E – Extremity warming: Gentle warming or massage of a cyanotic extremity increases peripheral blood flow, relieving peripheral cyanosis.
  • T – Time to check clubbing: Ascertain the presence or absence of clubbing in the digits.
  • O – Occurrence of cyanosis and clubbing: Frequent in congenital heart disease with right-to-left shunting, occasionally seen in pulmonary disease.
  • F – Fistulae and lung abscess: Pulmonary disease such as lung abscess or arteriovenous fistulae can cause cyanosis and clubbing.
  • C – Central cyanosis association: Central cyanosis isn’t associated with clubbed digits and usually develops acutely.
  • Y – Yield of blood examination: Determine Pao2 and Sao2 levels, perform spectroscopic examination to identify abnormal hemoglobin types critical for diagnosing cyanosis.
  • A – Abnormal hemoglobin: Spectroscopic examination helps identify abnormal hemoglobin types in cases with unclear mechanisms of cyanosis.
  • N – Noteworthy differential diagnosis: Differentiate cyanosis causes using critical hemoglobin analysis.
  • O – Overall evaluation: Consider all important features to arrive at the cause of cyanosis.
  • S – Seek professional advice: Consult a healthcare professional for accurate diagnosis and management
  • I – Important clues: Certain features aid in determining the cause of cyanosis.
  • S – Supportive evidence: Identify evidence of respiratory or cardiovascular disorders to assist in diagnosis.


Dr. Arin Nandi

Passionate About Medical Science & Helping Future Doctors Achieve Top Ranks In Medical Exams. He is professionally a dentist as well as a public health expert from JIPMER (1), (2)working in health department