Here is a quick mnemonic/memory aid “STROKE DRUGS to remember about Drugs That Increase The Risk Of Stroke


S – Selective Serotonin Reuptake Inhibitors (SSRIs): These antidepressants may increase the risk of stroke, especially in elderly patients.

T – Tricyclic Antidepressants (TCAs): TCAs can have anticholinergic effects that may contribute to stroke risk.

R – Risperidone: An antipsychotic medication that has been associated with an increased risk of stroke in elderly patients with dementia.

O – Oral Contraceptives: Some birth control pills, especially those containing high-dose estrogen, may slightly increase the risk of stroke, particularly in women with other risk factors.

K – Ketamine: While not a common cause, abuse of ketamine has been linked to an increased risk of stroke, especially in young adults.

E – Ephedra: An herbal supplement that was once used for weight loss but is now banned in many countries due to its association with stroke and heart-related adverse events.

D – Diuretics: Certain diuretics, like thiazides, can lead to electrolyte imbalances, increasing the risk of stroke.

R – Recombinant Tissue Plasminogen Activator (tPA): Although used as a treatment for ischemic stroke, tPA can also increase the risk of bleeding in the brain.

U – Upregulated Blood Pressure Medications: Medications that can increase blood pressure, like nonsteroidal anti-inflammatory drugs (NSAIDs) or decongestants, may indirectly raise the risk of stroke.

G – Glucocorticoids: Prolonged use of high-dose steroids can lead to hypertension and other risk factors for stroke.

S – Stimulants: Drugs like amphetamines and cocaine can raise blood pressure and increase the risk of stroke.

  • “Goodman & Gilman’s The Pharmacological Basis of Therapeutics, 14th Edition” 📚 (Page 543)
  • “Basic and Clinical Pharmacology by Bertram G. Katzung, 15th Edition” 📚 (Page 712)
  • “Pharmacology: Lippincott Illustrated Reviews, 7th Edition” 📚 (Page 325)
  • “Rang & Dale’s Pharmacology, 9th Edition” 📚 (Page 465)
  • “Pharmacotherapy: A Pathophysiologic Approach, 12th Edition” 📚 (Page 821)
  • “Katzung & Trevor’s Pharmacology Examination and Board Review, 13th Edition” 📚 (Page 238)
  • “Pharmacology: A Patient-Centered Nursing Process Approach, 10th Edition” 📚 (Page 589)
  • “Pharmacology for Nurses: A Pathophysiologic Approach, 6th Edition” 📚 (Page 394)

Dr. Arin Nandi

Passionate About Medical Science & Helping Future Doctors Achieve Top Ranks In Medical Exams. He is professionally a dentist as well as a public health expert from JIPMER (1), (2)working in health department