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Here is a quick mnemonic “DIAGNOSIS OF to remember about Differential Diagnosis Of Indigestion

This can be valuable for patients as well as medical doctors, nurses & students doing their clinical rounds. You can also find it very useful for med exams like USMLE, NExT Medical Step 1&2, MBBS, NEET PG, INI-CET, FMGE,MCAT & NCLEX exams

Differential Diagnosis Of Indigestion : How To Remember Easily ?

  • D – Differential Diagnosis: Gastroesophageal Reflux Disease, Heartburn, or regurgitation is reported weekly by 18–28% of the population, highlighting the prevalence of gastroesophageal reflux disease (GERD).
  • I – Incidence: Approximately 20% of the populace has dyspepsia at least six times yearly, but only 10–20% present to clinicians.
  • A – Absence of Organic Cause: Functional dyspepsia, the cause of symptoms in 70–80% of dyspeptic patients, is defined as bothersome postprandial fullness, early satiety, or epigastric pain or burning with symptom onset ≥6 months before diagnosis in the absence of organic cause.
  • G – Gastric Malignancies: Gastric malignancies include adenocarcinoma, which is prevalent in certain Asian societies, and lymphoma.
  • N – Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): The most common causes of ulcers are H. pylori infection and NSAID use.
  • O – Other Causes: Opportunistic fungal or viral esophageal infections may produce heartburn but more often cause odynophagia. Other causes of esophageal inflammation include eosinophilic esophagitis and pill esophagitis.
  • S – Small-Intestinal Bacterial Overgrowth: Small-intestinal bacterial overgrowth may cause dyspepsia, as well as bowel dysfunction, distention, and malabsorption.
  • I – Intolerance of Other Carbohydrates: Intolerance of other carbohydrates (e.g., fructose, sorbitol) produces similar symptoms.
  • S – Subdivisions of Functional Dyspepsia: Functional dyspepsia is subdivided into postprandial distress syndrome (61% of cases) and epigastric pain syndrome (18% of cases).
  • O – Overproduction of Gastrin: Zollinger-Ellison syndrome (Chap. 324) results from gastrin overproduction by an endocrine tumor.
  • F – Few Cases Result from Malignancy: Dyspeptic patients may seek care because of fear of cancer, but few cases result from malignancy.


Dr. Arin Nandi

Passionate About Medical Science & Helping Future Doctors Achieve Top Ranks In Medical Exams. He is professionally a dentist as well as a public health expert from JIPMER (1), (2)working in health department