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Here is a quick mnemonic “CAUSES OF DEMENTIA to remember about Causes Of Dementia

This can be valuable for patients as well as medical doctors, nurses & students doing their clinical rounds. You can also find it very useful for med exams like USMLE, MBBS, NEET PG, FMGE, NExT, MCAT & NCLEX exams

Causes Of Dementia : How To Remember Easily ?

  • C – Chronic intoxications, including alcohol and prescription drugs, are an important cause of dementia.
  • A – Aging is the single strongest risk factor for dementia, with prevalence increasing with age.
  • U – Uncommon but important causes of dementia 
  • S – Subtle cumulative decline in episodic memory is a common part of aging.
  • E – Education, hearing loss, traumatic brain injury, hypertension, diabetes mellitus, obesity, heavy alcohol use, smoking, depression, physical inactivity, and air pollution are modifiable risk factors associated with developing dementia.
  • S – Subjective cognitive decline refers to individuals who experience a decline from their cognitive baseline but perform within normal limits on formal neuropsychological testing.
  • O – Other disorders listed in Table 29-1 are uncommon but important, as many are reversible.
  • F – Factors predicting progression from mild cognitive impairment (MCI) to Alzheimer’s disease (AD) dementia include a prominent memory deficit, family history of dementia, presence of an Apo ε4 allele, small hippocampal volumes, cortical atrophy, low cerebrospinal fluid Aβ, elevated tau, and evidence of brain amyloid and tau deposition on PET imaging.
  • D – Depression, normal pressure hydrocephalus (NPH), and alcohol dependence are among the most common potentially reversible diagnoses in patients with cognitive impairment.
  • E – Each decade of life increases the prevalence of dementia, although it remains controversial whether dementia is an inevitable consequence of normal human aging.
  • M – Mixed pathology, especially in older individuals, is common and refers to the coexistence of different pathological causes of dementia.
  • E – Every patient should be assessed for medication side effects, as they are common and can contribute to cognitive impairment.
  • N – Neurodegenerative disorders such as Alzheimer’s disease (AD), dementia with Lewy bodies (DLB), frontotemporal dementia (FTD), and related disorders, Huntington’s disease (HD), and prion diseases are major causes of dementia.
  • T – The term rapidly progressive dementia (RPD) is used for illnesses that progress to dementia within a year, excluding confusional states related to toxic/metabolic conditions.
  • I – Irreversible and reversible disorders are classified as a useful approach to differential diagnosis of dementing illnesses.
  • A – AD is the most common cause of dementia in Western countries, accounting for more than half of all patients.


Dr. Arin Nandi

Passionate About Medical Science & Helping Future Doctors Achieve Top Ranks In Medical Exams. He is professionally a dentist as well as a public health expert from JIPMER (1), (2)working in health department