You are currently viewing Asperger Syndrome :‎ Medical Notes & Mindmap

Asperger Syndrome is a neurodevelopmental disorder that makes it hard to get along with other people, do things over and over again, and understand nonverbal cues.

People with Asperger Syndrome are often smarter than average and may be very good at certain things, like school or music. It is on the end of the autism spectrum called “high functioning.”

It is usually found in children, and boys are more likely to have it than girls. It is no longer a separate disorder in the DSM-5. Instead, it is now considered part of Autism Spectrum Disorder.

Asperger Syndrome :‎ [MEDNOTES+MINDMAP]

  • Definition :
    • A developmental disorder that affects a person’s ability to socialize and communicate effectively with others.
    • It is considered to be on the high-functioning end of the autism spectrum.
  • Epidemiology :
    • Affects an estimated 1 in every 250 individuals.
    • Higher prevalence in males than females.
    • Most commonly diagnosed in childhood, but can also be diagnosed in adulthood.
  • Natural history :
    • Lifelong condition that can affect an individual’s ability to function in various aspects of life.
    • With proper support and intervention, individuals can learn to manage their symptoms and lead fulfilling lives.
  • Classification :
    • Classified as a disorder on the autism spectrum.
    • High-functioning form of autism.
    • No specific stages or types of Asperger Syndrome.
    • Individuals may present with varying degrees of symptoms and impairment.
  • Risk Factors :

    • Genetic predisposition
    • Environmental factors (e.g. prenatal exposure to toxins)
    • Family history of autism spectrum disorder
  • Etiology/Causes :

    • Genetic mutations or variations
    • Abnormal brain development or functioning
    • Imbalanced neurotransmitters
  • Signs :

    • Difficulty with social interaction and communication
    • Repetitive behaviors and routines
    • Limited interests or preoccupations
    • Clumsy or uncoordinated movements
  • Symptoms :

    • Difficulty with nonverbal communication (e.g. facial expressions, body language)
    • Difficulty understanding and interpreting social cues
    • Difficulty with reciprocal conversation
    • Lack of interest in social activities
    • Repetitive or obsessive behaviors or routines
    • Intense interest in specific, narrow topics
  • Pathology/Pathogenesis :

    • Abnormal brain development or functioning in areas related to social interaction and communication
    • Imbalanced neurotransmitters (e.g. serotonin, dopamine)
    • Potential for abnormal connectivity or communication between different brain regions.
  • Diagnosis :
    • Typically diagnosed through observation of behavior and communication patterns, as well as ruling out other conditions
    • No specific lab tests available for diagnosis
  • Tests Required :
    • Behavioral assessments and developmental assessments to evaluate social interactions and communication abilities
    • Autism diagnostic observation schedule (ADOS) and autism diagnostic interview-revised (ADI-R) commonly used
  • Associated with :
    • Autism Spectrum Disorder (ASD)
    • Difficulty with social interactions and communication
    • Repetitive behaviors and interests
  • Similar diseases/syndromes :
    • High-functioning autism
    • Pervasive Developmental Disorder-Not Otherwise Specified (PDD-NOS)
  • Treatment :
    • Behavioral therapy and social skills training
    • Speech and language therapy
    • Occupational therapy to improve daily living skills
    • Medications to manage associated symptoms such as anxiety or ADHD.

Dr. Arin Nandi

Passionate About Medical Science & Helping Future Doctors Achieve Top Ranks In Medical Exams. He is professionally a dentist as well as a public health expert from JIPMER working in department