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Anterior spinal artery syndrome is a rare neurological condition that happens when the blood flow to the front of the spinal cord is cut off or damaged by a blocked or damaged anterior spinal artery. This can make the body lose the ability to feel and move below the point where the blockage is. Most of the time, a blood clot, an aneurysm, or a serious injury to the spine is what causes this syndrome. Some medical conditions, like aortic dissection or spinal arteriovenous malformation, can also cause it.

Anterior Spinal Artery Syndrome :‎ [MEDNOTES+MINDMAP]

  • Definition:

    • Anterior Spinal Artery Syndrome is a rare neurological condition characterized by damage to the anterior spinal artery, which supplies blood to the front part of the spinal cord.
    • This can lead to a variety of symptoms, including weakness, numbness, and paralysis in the affected areas of the body.
  • Epidemiology:

    • The prevalence of Anterior Spinal Artery Syndrome is unknown, as it is a rare condition.
    • It can occur at any age, but is more common in older individuals.
  • Natural history:

    • The natural history of Anterior Spinal Artery Syndrome varies depending on the severity of the damage to the spinal cord.
    • In mild cases, symptoms may resolve on their own or with treatment.
    • In severe cases, permanent paralysis or other disabilities may occur.
  • Classification:

    • Anterior Spinal Artery Syndrome can be classified based on the location and extent of the damage to the spinal cord.
    • Types of Anterior Spinal Artery Syndrome include complete, incomplete, and partial.
    • The stage of Anterior Spinal Artery Syndrome is determined by the severity of the symptoms and their impact on the individual’s ability to function.

Risk Factors:

  • Aging
  • Hypertension
  • Atherosclerosis
  • Trauma or injury to the spine
  • Spinal surgery
  • Spinal infections
  • Spinal tumors
  • Vascular abnormalities
  • Genetic predisposition


  • Occlusion or narrowing of the anterior spinal artery
  • Disruption of the blood supply to the spinal cord
  • Inflammation or infection in the spinal cord


  • Weakness or paralysis in the legs
  • Loss of reflexes in the legs
  • Loss of sensation in the legs or lower body
  • Loss of bowel or bladder control
  • Difficulty walking or standing


  • Back pain
  • Numbness or tingling in the legs or lower body
  • Difficulty moving the legs or lower body
  • Difficulty with balance or coordination
  • Difficulty with urination or defecation


  • Damage or death of spinal cord tissue due to reduced blood supply
  • Inflammation or infection in the spinal cord
  • Formation of scar tissue in the spinal cord
  • Disruption of nerve pathways in the spinal cord


  • Clinical examination
  • MRI scan to assess blood flow in the spinal cord
  • Angiography to visualize the blood vessels in the spinal cord

Tests Required:

  • Blood tests to rule out other causes of spinal cord dysfunction
  • Electromyography to assess nerve and muscle function

Associated with:

  • Aortic aneurysm
  • Aortic dissection
  • Atherosclerosis
  • Spinal cord injury

Similar diseases/syndromes:

  • Posterior Spinal Artery Syndrome
  • Central Cord Syndrome
  • Brown-Séquard Syndrome


  • Emergency surgery to repair aortic aneurysm or dissection
  • Blood pressure control to reduce strain on the aorta
  • Physical therapy to improve muscle strength and mobility
  • Medications to manage pain and inflammation
  • Rehabilitation to improve functional abilities

Dr. Arin Nandi

Passionate About Medical Science & Helping Future Doctors Achieve Top Ranks In Medical Exams. He is professionally a dentist as well as a public health expert from JIPMER working in department